3zdl: Difference between revisions
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{{STRUCTURE_3zdl| PDB=3zdl | SCENE= }} | {{STRUCTURE_3zdl| PDB=3zdl | SCENE= }} | ||
===Vinculin head (1-258) in complex with a RIAM fragment=== | ===Vinculin head (1-258) in complex with a RIAM fragment=== | ||
{{ABSTRACT_PUBMED_23389036}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[http://www.uniprot.org/uniprot/AB1IP_HUMAN AB1IP_HUMAN]] Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.<ref>PMID:14530287</ref> <ref>PMID:15469846</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3zdl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZDL OCA]. | [[3zdl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZDL OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Barsukov, I L.]] | [[Category: Barsukov, I L.]] | ||
