2a2z: Difference between revisions

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[[Image:2a2z.gif|left|200px]]<br /><applet load="2a2z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a2z.gif|left|200px]]
caption="2a2z, resolution 3.02&Aring;" />
 
'''Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate'''<br />
{{Structure
|PDB= 2a2z |SIZE=350|CAPTION= <scene name='initialview01'>2a2z</scene>, resolution 3.02&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=DCZ:2'-DEOXYCYTIDINE'>DCZ</scene> and <scene name='pdbligand=UDP:URIDINE-5'-DIPHOSPHATE'>UDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxycytidine_kinase Deoxycytidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.74 2.7.1.74]
|GENE= DCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A2Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=DCZ:'>DCZ</scene> and <scene name='pdbligand=UDP:'>UDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Deoxycytidine_kinase Deoxycytidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.74 2.7.1.74] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2Z OCA].  
2A2Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2Z OCA].  


==Reference==
==Reference==
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization., Godsey MH, Ort S, Sabini E, Konrad M, Lavie A, Biochemistry. 2006 Jan 17;45(2):452-61. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16401075 16401075]
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization., Godsey MH, Ort S, Sabini E, Konrad M, Lavie A, Biochemistry. 2006 Jan 17;45(2):452-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16401075 16401075]
[[Category: Deoxycytidine kinase]]
[[Category: Deoxycytidine kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: uridine diphosphate]]
[[Category: uridine diphosphate]]


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