4f3k: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4f3k|  PDB=4f3k  |  SCENE=  }}
===Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A===


The entry 4f3k is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/E8NLP5_SALET E8NLP5_SALET]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]


Authors: Haapalainen, A.M., Thomas, K., Bonanno, J.B., Almo, S.C., Schramm, V.L.
==About this Structure==
 
[[4f3k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_choleraesuis_str._scsa50 Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3K OCA].
Description: Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A
[[Category: Adenosylhomocysteine nucleosidase]]
[[Category: Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]]
[[Category: Almo, S C.]]
[[Category: Bonanno, J B.]]
[[Category: Haapalainen, A M.]]
[[Category: Schramm, V L.]]
[[Category: Thomas, K.]]
[[Category: 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase]]
[[Category: Acting on glycosyl bond]]
[[Category: Adenosylhomocysteine nucleosidase activity]]
[[Category: Hydrolase activity]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: L-methionine biosynthetic process from s-adenosylmethionine]]
[[Category: L-methionine salvage from methylthioadenosine]]
[[Category: Methylthioadenosine nucleosidase activity]]

Revision as of 07:49, 2 May 2013

Template:STRUCTURE 4f3k

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A

Function

[E8NLP5_SALET] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]

About this Structure

4f3k is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50. Full crystallographic information is available from OCA.

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