2a39: Difference between revisions

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[[Image:2a39.jpg|left|200px]]<br /><applet load="2a39" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a39.jpg|left|200px]]
caption="2a39, resolution 2.2&Aring;" />
 
'''HUMICOLA INSOLENS ENDOCELLULASE EGI NATIVE STRUCTURE'''<br />
{{Structure
|PDB= 2a39 |SIZE=350|CAPTION= <scene name='initialview01'>2a39</scene>, resolution 2.2&Aring;
|SITE= <scene name='pdbsite=ACI:Catalytic+Acid/Base'>ACI</scene> and <scene name='pdbsite=NUC:Catalytic+Nucleophile+As+Identified+By+2-Fluorocellobios+...'>NUC</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]
|GENE= POTENTIAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=34413 Humicola insolens])
}}
 
'''HUMICOLA INSOLENS ENDOCELLULASE EGI NATIVE STRUCTURE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens] with <scene name='pdbligand=NAG:'>NAG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] Known structural/functional Sites: <scene name='pdbsite=ACI:Catalytic+Acid/Base'>ACI</scene> and <scene name='pdbsite=NUC:Catalytic+Nucleophile+As+Identified+By+2-Fluorocellobios+...'>NUC</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A39 OCA].  
2A39 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A39 OCA].  


==Reference==
==Reference==
Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 A resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate., MacKenzie LF, Sulzenbacher G, Divne C, Jones TA, Woldike HF, Schulein M, Withers SG, Davies GJ, Biochem J. 1998 Oct 15;335 ( Pt 2):409-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761741 9761741]
Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 A resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate., MacKenzie LF, Sulzenbacher G, Divne C, Jones TA, Woldike HF, Schulein M, Withers SG, Davies GJ, Biochem J. 1998 Oct 15;335 ( Pt 2):409-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9761741 9761741]
[[Category: Cellulase]]
[[Category: Cellulase]]
[[Category: Humicola insolens]]
[[Category: Humicola insolens]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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