4ilh: Difference between revisions
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{{STRUCTURE_4ilh| PDB=4ilh | SCENE= }} | |||
===Crystal structure of an Aar2p C-terminal deletion mutant in conplex with Prp8p RNaseH=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref><ref>PMID:9150140</ref><ref>PMID:12773561</ref><ref>PMID:18779563</ref> [[http://www.uniprot.org/uniprot/AAR2_YEAST AAR2_YEAST]] Involved in splicing pre-mRNA of the A1 cistron and other genes that are important for cell growth. | |||
==About this Structure== | |||
[[4ilh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILH OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae s288c]] | |||
[[Category: Heroven, A C.]] | |||
[[Category: Santos, K F.]] | |||
[[Category: Wahl, M C.]] | |||
[[Category: Weber, G.]] | |||
[[Category: Aar2]] | |||
[[Category: Prp8]] | |||
[[Category: Splicing]] | |||
[[Category: U5 snrnp assembly]] | |||