2a45: Difference between revisions

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[[Image:2a45.gif|left|200px]]<br /><applet load="2a45" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a45.gif|left|200px]]
caption="2a45, resolution 3.65&Aring;" />
 
'''Crystal structure of the complex between thrombin and the central "E" region of fibrin'''<br />
{{Structure
|PDB= 2a45 |SIZE=350|CAPTION= <scene name='initialview01'>2a45</scene>, resolution 3.65&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''Crystal structure of the complex between thrombin and the central "E" region of fibrin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A45 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1QVH. The following page contains interesting information on the relation of 2A45 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb83_1.html Fibrin]]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A45 OCA].  
2A45 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1QVH. The following page contains interesting information on the relation of 2A45 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb83_1.html Fibrin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A45 OCA].  


==Reference==
==Reference==
Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly., Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L, Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16533041 16533041]
Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly., Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L, Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16533041 16533041]
[[Category: Fibrin]]
[[Category: Fibrin]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Pechik, I.]]
[[Category: Pechik, I.]]
[[Category: PO4]]
[[Category: PO4]]
[[Category: coiled coils]]
[[Category: coiled coil]]
[[Category: disulfide rings]]
[[Category: disulfide ring]]
[[Category: fibrin]]
[[Category: fibrin]]
[[Category: fragment e]]
[[Category: fragment e]]
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[[Category: thrombin-fibrin complex]]
[[Category: thrombin-fibrin complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:24 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:45:09 2008''
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