2lpn: Difference between revisions
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{{STRUCTURE_2lpn| PDB=2lpn | SCENE= }} | {{STRUCTURE_2lpn| PDB=2lpn | SCENE= }} | ||
===Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF)=== | ===Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF)=== | ||
{{ABSTRACT_PUBMED_22528768}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN]] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[2lpn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPN OCA]. | [[2lpn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPN OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:022528768</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Almeida, M S.]] | [[Category: Almeida, M S.]] | ||
Revision as of 06:30, 20 June 2013
Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF)
Template:ABSTRACT PUBMED 22528768
Function
[CDNF_HUMAN] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
About this Structure
2lpn is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Latge C, Cabral KM, Almeida MS, Foguel D. (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Biomol NMR Assign. 2012 Apr 18. PMID:22528768 doi:10.1007/s12104-012-9388-8
