2a6h: Difference between revisions

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[[Image:2a6h.gif|left|200px]]<br /><applet load="2a6h" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a6h.gif|left|200px]]
caption="2a6h, resolution 2.40&Aring;" />
 
'''Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin'''<br />
{{Structure
|PDB= 2a6h |SIZE=350|CAPTION= <scene name='initialview01'>2a6h</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=STD:STREPTOLYDIGIN'>STD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6]
|GENE=
}}
 
'''Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A6H is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=STD:'>STD</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6H OCA].  
2A6H is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6H OCA].  


==Reference==
==Reference==
Structural basis of transcription inhibition by antibiotic streptolydigin., Temiakov D, Zenkin N, Vassylyeva MN, Perederina A, Tahirov TH, Kashkina E, Savkina M, Zorov S, Nikiforov V, Igarashi N, Matsugaki N, Wakatsuki S, Severinov K, Vassylyev DG, Mol Cell. 2005 Sep 2;19(5):655-66. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16167380 16167380]
Structural basis of transcription inhibition by antibiotic streptolydigin., Temiakov D, Zenkin N, Vassylyeva MN, Perederina A, Tahirov TH, Kashkina E, Savkina M, Zorov S, Nikiforov V, Igarashi N, Matsugaki N, Wakatsuki S, Severinov K, Vassylyev DG, Mol Cell. 2005 Sep 2;19(5):655-66. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16167380 16167380]
[[Category: DNA-directed RNA polymerase]]
[[Category: DNA-directed RNA polymerase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: rsgi]]
[[Category: rsgi]]
[[Category: streptolydigin]]
[[Category: streptolydigin]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: transcription regulation]]
[[Category: transcription regulation]]


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