2aa2: Difference between revisions

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[[Image:2aa2.gif|left|200px]]<br /><applet load="2aa2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2aa2.gif|left|200px]]
caption="2aa2, resolution 1.950&Aring;" />
 
'''Mineralocorticoid Receptor with Bound Aldosterone'''<br />
{{Structure
|PDB= 2aa2 |SIZE=350|CAPTION= <scene name='initialview01'>2aa2</scene>, resolution 1.950&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=AS4:ALDOSTERONE'>AS4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= NR3C2, MCR, MLR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Mineralocorticoid Receptor with Bound Aldosterone'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AA2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=AS4:'>AS4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA2 OCA].  
2AA2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA2 OCA].  


==Reference==
==Reference==
A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor., Bledsoe RK, Madauss KP, Holt JA, Apolito CJ, Lambert MH, Pearce KH, Stanley TB, Stewart EL, Trump RP, Willson TM, Williams SP, J Biol Chem. 2005 Sep 2;280(35):31283-93. Epub 2005 Jun 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15967794 15967794]
A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor., Bledsoe RK, Madauss KP, Holt JA, Apolito CJ, Lambert MH, Pearce KH, Stanley TB, Stewart EL, Trump RP, Willson TM, Williams SP, J Biol Chem. 2005 Sep 2;280(35):31283-93. Epub 2005 Jun 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15967794 15967794]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: steroid receptor]]
[[Category: steroid receptor]]


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