2aa9: Difference between revisions

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[[Image:2aa9.gif|left|200px]]<br /><applet load="2aa9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2aa9.gif|left|200px]]
caption="2aa9, resolution 1.5&Aring;" />
 
'''EPSP synthase liganded with shikimate'''<br />
{{Structure
|PDB= 2aa9 |SIZE=350|CAPTION= <scene name='initialview01'>2aa9</scene>, resolution 1.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19]
|GENE= aroA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''EPSP synthase liganded with shikimate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AA9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SKM:'>SKM</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-phosphoshikimate_1-carboxyvinyltransferase 3-phosphoshikimate 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.19 2.5.1.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA9 OCA].  
2AA9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA9 OCA].  


==Reference==
==Reference==
Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate., Priestman MA, Healy ML, Funke T, Becker A, Schonbrunn E, FEBS Lett. 2005 Oct 24;579(25):5773-80. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16225867 16225867]
Molecular basis for the glyphosate-insensitivity of the reaction of 5-enolpyruvylshikimate 3-phosphate synthase with shikimate., Priestman MA, Healy ML, Funke T, Becker A, Schonbrunn E, FEBS Lett. 2005 Oct 24;579(25):5773-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16225867 16225867]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: 3-phosphoshikimate 1-carboxyvinyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: inside-out alpha/beta barrel]]
[[Category: inside-out alpha/beta barrel]]


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