3anx: Difference between revisions
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{{STRUCTURE_3anx| PDB=3anx | SCENE= }} | {{STRUCTURE_3anx| PDB=3anx | SCENE= }} | ||
===Crystal structure of triamine/agmatine aminopropyltransferase (SPEE) from thermus thermophilus, complexed with MTA=== | ===Crystal structure of triamine/agmatine aminopropyltransferase (SPEE) from thermus thermophilus, complexed with MTA=== | ||
{{ABSTRACT_PUBMED_21458463}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SPEE_THET8 SPEE_THET8]] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.<ref>PMID:21458463</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3anx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3anx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ANX OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:021458463</ref><references group="xtra"/><references/> | |||
[[Category: Spermidine synthase]] | [[Category: Spermidine synthase]] | ||
[[Category: | [[Category: Thet8]] | ||
[[Category: Ganbe, T.]] | [[Category: Ganbe, T.]] | ||
[[Category: Kumasaka, T.]] | [[Category: Kumasaka, T.]] | ||
Revision as of 06:31, 29 January 2014
Crystal structure of triamine/agmatine aminopropyltransferase (SPEE) from thermus thermophilus, complexed with MTA
Template:ABSTRACT PUBMED 21458463
Function
[SPEE_THET8] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor. Has broad substrate specificity. Is also active with agmatine and norspermidine. Has lower activity with homospermidine, mitsubishine and thermine.[1]
About this Structure
3anx is a 2 chain structure with sequence from Thet8. Full crystallographic information is available from OCA.
Reference
- Ohnuma M, Ganbe T, Terui Y, Niitsu M, Sato T, Tanaka N, Tamakoshi M, Samejima K, Kumasaka T, Oshima T. Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus. J Mol Biol. 2011 May 20;408(5):971-86. Epub 2011 Mar 31. PMID:21458463 doi:https://dx.doi.org/10.1016/j.jmb.2011.03.025
- ↑ Ohnuma M, Ganbe T, Terui Y, Niitsu M, Sato T, Tanaka N, Tamakoshi M, Samejima K, Kumasaka T, Oshima T. Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus. J Mol Biol. 2011 May 20;408(5):971-86. Epub 2011 Mar 31. PMID:21458463 doi:https://dx.doi.org/10.1016/j.jmb.2011.03.025
