2ad5: Difference between revisions

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[[Image:2ad5.jpg|left|200px]]<br /><applet load="2ad5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ad5.jpg|left|200px]]
caption="2ad5, resolution 2.8&Aring;" />
 
'''Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution.'''<br />
{{Structure
|PDB= 2ad5 |SIZE=350|CAPTION= <scene name='initialview01'>2ad5</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=CTP:CYTIDINE-5'-TRIPHOSPHATE'>CTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/CTP_synthase CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2]
|GENE=
}}
 
'''Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AD5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=CTP:'>CTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/CTP_synthase CTP synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AD5 OCA].  
2AD5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AD5 OCA].  


==Reference==
==Reference==
Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex., Endrizzi JA, Kim H, Anderson PM, Baldwin EP, Biochemistry. 2005 Oct 18;44(41):13491-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16216072 16216072]
Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex., Endrizzi JA, Kim H, Anderson PM, Baldwin EP, Biochemistry. 2005 Oct 18;44(41):13491-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16216072 16216072]
[[Category: CTP synthase]]
[[Category: CTP synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: rossman fold]]
[[Category: rossman fold]]


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