2m5b: Difference between revisions
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{{STRUCTURE_2m5b| PDB=2m5b | SCENE= }} | |||
===The NMR structure of the BID-BAK complex=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN]] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref> | |||
==About this Structure== | |||
[[2m5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5B OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Grace, C R.]] | |||
[[Category: Green, D R.]] | |||
[[Category: Kriwacki, R W.]] | |||
[[Category: Moldoveanu, T.]] | |||
[[Category: Apoptosis]] | |||
[[Category: Bcl-2 family effector bak]] | |||
[[Category: Bh3-only protein bid]] | |||
[[Category: Effector direct activation]] | |||
[[Category: Mitochondrial outer membrane premeabilization]] | |||
[[Category: Nmr solution structure of bid-bak complex]] | |||