2ag2: Difference between revisions

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[[Image:2ag2.gif|left|200px]]<br /><applet load="2ag2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ag2.gif|left|200px]]
caption="2ag2, resolution 2.00&Aring;" />
 
'''Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine'''<br />
{{Structure
|PDB= 2ag2 |SIZE=350|CAPTION= <scene name='initialview01'>2ag2</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=CH5:2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM'>CH5</scene>, <scene name='pdbligand=LP3:(7S)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM+4-OXIDE'>LP3</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene> and <scene name='pdbligand=IPA:ISOPROPYL ALCOHOL'>IPA</scene>
|ACTIVITY=
|GENE= GM2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AG2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=EPE:'>EPE</scene>, <scene name='pdbligand=CH5:'>CH5</scene>, <scene name='pdbligand=LP3:'>LP3</scene>, <scene name='pdbligand=OLA:'>OLA</scene>, <scene name='pdbligand=MYR:'>MYR</scene>, <scene name='pdbligand=DAO:'>DAO</scene> and <scene name='pdbligand=IPA:'>IPA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AG2 OCA].  
2AG2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AG2 OCA].  


==Reference==
==Reference==
Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity., Wright CS, Mi LZ, Lee S, Rastinejad F, Biochemistry. 2005 Oct 18;44(41):13510-21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16216074 16216074]
Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity., Wright CS, Mi LZ, Lee S, Rastinejad F, Biochemistry. 2005 Oct 18;44(41):13510-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16216074 16216074]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: phospholipid-protein complex]]
[[Category: phospholipid-protein complex]]


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