4il8: Difference between revisions
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{{STRUCTURE_4il8| PDB=4il8 | SCENE= }} | |||
===Crystal structure of an H329A mutant of p. aeruginosa PMM/PGM=== | |||
{{ABSTRACT_PUBMED_23517223}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/ALGC_PSEAE ALGC_PSEAE]] The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity, and for biofilm production.<ref>PMID:7515870</ref> <ref>PMID:10481091</ref> | |||
==About this Structure== | |||
[[4il8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IL8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023517223</ref><references group="xtra"/><references/> | |||
[[Category: Pseudomonas aeruginosa pao1]] | |||
[[Category: Beamer, L.]] | |||
[[Category: Furdui, C.]] | |||
[[Category: Lee, Y.]] | |||
[[Category: Mehra-Chaudhary, R.]] | |||
[[Category: A-d-phosphohexomutase]] | |||
[[Category: Isomerase]] | |||
[[Category: Phosphoserine]] | |||