2ai1: Difference between revisions

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[[Image:2ai1.gif|left|200px]]<br /><applet load="2ai1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ai1.gif|left|200px]]
caption="2ai1, resolution 2.00&Aring;" />
 
'''Purine nucleoside phosphorylase from calf spleen'''<br />
{{Structure
|PDB= 2ai1 |SIZE=350|CAPTION= <scene name='initialview01'>2ai1</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene> and <scene name='pdbligand=P1G:((2R,4R,6R,6AS)-4-(2-AMINO-6-OXO-1,6-DIHYDROPURIN-9-YL)-6-(HYDROXYMETHYL)-TETRAHYDROFURO[3,4-D][1,3]DIOXOL-2-YL)METHYLPHOSPHONIC ACID'>P1G</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
|GENE=
}}
 
'''Purine nucleoside phosphorylase from calf spleen'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AI1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=144:'>144</scene> and <scene name='pdbligand=P1G:'>P1G</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AI1 OCA].  
2AI1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AI1 OCA].  


==Reference==
==Reference==
Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase., Toms AV, Wang W, Li Y, Ganem B, Ealick SE, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1449-58. Epub 2005, Oct 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16239721 16239721]
Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase., Toms AV, Wang W, Li Y, Ganem B, Ealick SE, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1449-58. Epub 2005, Oct 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16239721 16239721]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
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[[Category: purine nucleoside phosphorylase]]
[[Category: purine nucleoside phosphorylase]]


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