2al4: Difference between revisions

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[[Image:2al4.gif|left|200px]]<br /><applet load="2al4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2al4.gif|left|200px]]
caption="2al4, resolution 1.70&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614.'''<br />
{{Structure
|PDB= 2al4 |SIZE=350|CAPTION= <scene name='initialview01'>2al4</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CX6:2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE'>CX6</scene> and <scene name='pdbligand=QUS:(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID'>QUS</scene>
|ACTIVITY=
|GENE= Gria2, Glur2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AL4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CX6:'>CX6</scene> and <scene name='pdbligand=QUS:'>QUS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AL4 OCA].  
2AL4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AL4 OCA].  


==Reference==
==Reference==
Mechanism of positive allosteric modulators acting on AMPA receptors., Jin R, Clark S, Weeks AM, Dudman JT, Gouaux E, Partin KM, J Neurosci. 2005 Sep 28;25(39):9027-36. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16192394 16192394]
Mechanism of positive allosteric modulators acting on AMPA receptors., Jin R, Clark S, Weeks AM, Dudman JT, Gouaux E, Partin KM, J Neurosci. 2005 Sep 28;25(39):9027-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16192394 16192394]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: s1s2]]
[[Category: s1s2]]


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