2ama: Difference between revisions

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[[Image:2ama.gif|left|200px]]<br /><applet load="2ama" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ama.gif|left|200px]]
caption="2ama, resolution 1.90&Aring;" />
 
'''Crystal structure of human androgen receptor ligand binding domain in complex with dihydrotestosterone'''<br />
{{Structure
|PDB= 2ama |SIZE=350|CAPTION= <scene name='initialview01'>2ama</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>
|ACTIVITY=
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human androgen receptor ligand binding domain in complex with dihydrotestosterone'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AMA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=DHT:'>DHT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMA OCA].  
2AMA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMA OCA].  


==Reference==
==Reference==
Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity., Pereira de Jesus-Tran K, Cote PL, Cantin L, Blanchet J, Labrie F, Breton R, Protein Sci. 2006 May;15(5):987-99. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16641486 16641486]
Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity., Pereira de Jesus-Tran K, Cote PL, Cantin L, Blanchet J, Labrie F, Breton R, Protein Sci. 2006 May;15(5):987-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16641486 16641486]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: nuclear receptor]]
[[Category: nuclear receptor]]


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