2aou: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2aou.gif|left|200px]]<br /><applet load="2aou" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2aou.gif|left|200px]]
caption="2aou, resolution 2.3&Aring;" />
 
'''Histamine Methyltransferase Complexed with the Antimalarial Drug Amodiaquine'''<br />
{{Structure
|PDB= 2aou |SIZE=350|CAPTION= <scene name='initialview01'>2aou</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Histamine_N-methyltransferase Histamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.8 2.1.1.8]
|GENE= HNMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Histamine Methyltransferase Complexed with the Antimalarial Drug Amodiaquine'''
 


==Overview==
==Overview==
Line 10: Line 19:


==About this Structure==
==About this Structure==
2AOU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CQA:'>CQA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Histamine_N-methyltransferase Histamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.8 2.1.1.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOU OCA].  
2AOU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOU OCA].  


==Reference==
==Reference==
Structural basis for inhibition of histamine N-methyltransferase by diverse drugs., Horton JR, Sawada K, Nishibori M, Cheng X, J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16168438 16168438]
Structural basis for inhibition of histamine N-methyltransferase by diverse drugs., Horton JR, Sawada K, Nishibori M, Cheng X, J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16168438 16168438]
[[Category: Histamine N-methyltransferase]]
[[Category: Histamine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 25: Line 34:
[[Category: protein-drug complex]]
[[Category: protein-drug complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:25 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:52:08 2008''
Retrieved from "https://proteopedia.org/2aou"