2ao2: Difference between revisions

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[[Image:2ao2.gif|left|200px]]<br /><applet load="2ao2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ao2.gif|left|200px]]
caption="2ao2, resolution 2.070&Aring;" />
 
'''The 2.07 Angstrom crystal structure of Mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactions'''<br />
{{Structure
|PDB= 2ao2 |SIZE=350|CAPTION= <scene name='initialview01'>2ao2</scene>, resolution 2.070&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5]
|GENE= Rv1885c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''The 2.07 Angstrom crystal structure of Mycobacterium tuberculosis chorismate mutase reveals unexpected gene duplication and suggests a role in host-pathogen interactions'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AO2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=TRP:'>TRP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AO2 OCA].  
2AO2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AO2 OCA].  


==Reference==
==Reference==
The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions., Qamra R, Prakash P, Aruna B, Hasnain SE, Mande SC, Biochemistry. 2006 Jun 13;45(23):6997-7005. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16752890 16752890]
The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions., Qamra R, Prakash P, Aruna B, Hasnain SE, Mande SC, Biochemistry. 2006 Jun 13;45(23):6997-7005. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16752890 16752890]
[[Category: Chorismate mutase]]
[[Category: Chorismate mutase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]
[[Category: tryptophan]]
[[Category: tryptophan]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:27 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:51:55 2008''