2aq9: Difference between revisions

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[[Image:2aq9.gif|left|200px]]<br /><applet load="2aq9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2aq9.gif|left|200px]]
caption="2aq9, resolution 1.80&Aring;" />
 
'''Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP'''<br />
{{Structure
|PDB= 2aq9 |SIZE=350|CAPTION= <scene name='initialview01'>2aq9</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=DMS:DIMETHYL SULFOXIDE'>DMS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine_O-acyltransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.129 2.3.1.129]
|GENE= lpxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AQ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=DMS:'>DMS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine_O-acyltransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.129 2.3.1.129] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ9 OCA].  
2AQ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ9 OCA].  


==Reference==
==Reference==
Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide., Williams AH, Immormino RM, Gewirth DT, Raetz CR, Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10877-82. Epub 2006 Jul 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16835299 16835299]
Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide., Williams AH, Immormino RM, Gewirth DT, Raetz CR, Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10877-82. Epub 2006 Jul 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16835299 16835299]
[[Category: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase]]
[[Category: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: acp]]
[[Category: acp]]
[[Category: acyl acp]]
[[Category: acyl acp]]
[[Category: lipid a]]
[[Category: lipid some]]
[[Category: lpxa]]
[[Category: lpxa]]
[[Category: peptide inhibitor]]
[[Category: peptide inhibitor]]
[[Category: udp-glcnac]]
[[Category: udp-glcnac]]


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