4h4f: Difference between revisions
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{{STRUCTURE_4h4f| PDB=4h4f | SCENE= }} | {{STRUCTURE_4h4f| PDB=4h4f | SCENE= }} | ||
===Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis=== | |||
{{ABSTRACT_PUBMED_23430245}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CTRC_HUMAN CTRC_HUMAN]] Hereditary chronic pancreatitis. Note=Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CTRC_HUMAN CTRC_HUMAN]] Has chymotrypsin-type protease activity and hypocalcemic activity. [[http://www.uniprot.org/uniprot/ICIC_HIRME ICIC_HIRME]] Inhibits both elastase and cathepsin G. | |||
==About this Structure== | ==About this Structure== | ||
Revision as of 09:33, 24 April 2013
Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis
Template:ABSTRACT PUBMED 23430245
Disease
[CTRC_HUMAN] Hereditary chronic pancreatitis. Note=Genetic variations in CTRC can predispose to chronic pancreatitis by diminishing its protective trypsin-degrading activity.
Function
[CTRC_HUMAN] Has chymotrypsin-type protease activity and hypocalcemic activity. [ICIC_HIRME] Inhibits both elastase and cathepsin G.
About this Structure
4h4f is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
