4hva: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hva|  PDB=4hva  |  SCENE=  }}
===Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6===
{{ABSTRACT_PUBMED_23227217}}


The entry 4hva is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.


Authors: Murray, J.M., Steffek, M.
==About this Structure==
 
[[4hva]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HVA OCA].
Description: Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6
[[Category: Caspase-6]]
[[Category: Homo sapiens]]
[[Category: Murray, J M.]]
[[Category: Steffek, M.]]
[[Category: Active]]
[[Category: Caspase]]
[[Category: Caspase-6]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]
[[Category: Ternary complex]]
[[Category: Uncompetitive inhibition]]
[[Category: Veid]]