3j2u: Difference between revisions
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{{STRUCTURE_3j2u| PDB=3j2u | SCENE= }} | {{STRUCTURE_3j2u| PDB=3j2u | SCENE= }} | ||
===Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule=== | ===Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule=== | ||
{{ABSTRACT_PUBMED_23434508}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KI10A_DROME KI10A_DROME]] Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux".<ref>PMID:14681690</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). [[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
==About this Structure== | ==About this Structure== | ||
[[3j2u]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2U OCA]. | [[3j2u]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2U OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Gekko coi]] | [[Category: Gekko coi]] | ||
Revision as of 21:57, 10 April 2013
Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule
Template:ABSTRACT PUBMED 23434508
Function
[KI10A_DROME] Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux".[1] [TBB2B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). [TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
About this Structure
3j2u is a 5 chain structure with sequence from Bos taurus and Gekko coi. Full crystallographic information is available from OCA.
Reference
- ↑ Rogers GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, Vale RD, Scholey JM, Sharp DJ. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature. 2004 Jan 22;427(6972):364-70. Epub 2003 Dec 14. PMID:14681690 doi:10.1038/nature02256
