2b0q: Difference between revisions

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[[Image:2b0q.gif|left|200px]]<br /><applet load="2b0q" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2b0q.gif|left|200px]]
caption="2b0q, resolution 2.700&Aring;" />
 
'''Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Neomycin B Complex'''<br />
{{Structure
|PDB= 2b0q |SIZE=350|CAPTION= <scene name='initialview01'>2b0q</scene>, resolution 2.700&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=NMY:NEOMYCIN'>NMY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Kanamycin_kinase Kanamycin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.95 2.7.1.95]
|GENE= aphA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 Enterococcus faecalis])
}}
 
'''Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Neomycin B Complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2B0Q is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=NMY:'>NMY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1L8U. Active as [http://en.wikipedia.org/wiki/Kanamycin_kinase Kanamycin kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.95 2.7.1.95] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0Q OCA].  
2B0Q is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. This structure supersedes the now removed PDB entry 1L8U. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0Q OCA].  


==Reference==
==Reference==
Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry., Fong DH, Berghuis AM, EMBO J. 2002 May 15;21(10):2323-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12006485 12006485]
Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry., Fong DH, Berghuis AM, EMBO J. 2002 May 15;21(10):2323-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12006485 12006485]
[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
[[Category: Kanamycin kinase]]
[[Category: Kanamycin kinase]]
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[[Category: protein kinase-like]]
[[Category: protein kinase-like]]


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