2b1g: Difference between revisions

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[[Image:2b1g.gif|left|200px]]<br /><applet load="2b1g" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2b1g.gif|left|200px]]
caption="2b1g, resolution 2.100&Aring;" />
 
'''Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase'''<br />
{{Structure
|PDB= 2b1g |SIZE=350|CAPTION= <scene name='initialview01'>2b1g</scene>, resolution 2.100&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=13A:7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE'>13A</scene>
|ACTIVITY=
|GENE= ATIC, PURH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])
}}
 
'''Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2B1G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=13A:'>13A</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B1G OCA].  
2B1G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B1G OCA].  


==Reference==
==Reference==
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase., Xu L, Chong Y, Hwang I, D'Onofrio A, Amore K, Beardsley GP, Li C, Olson AJ, Boger DL, Wilson IA, J Biol Chem. 2007 Apr 27;282(17):13033-46. Epub 2007 Feb 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17324932 17324932]
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase., Xu L, Chong Y, Hwang I, D'Onofrio A, Amore K, Beardsley GP, Li C, Olson AJ, Boger DL, Wilson IA, J Biol Chem. 2007 Apr 27;282(17):13033-46. Epub 2007 Feb 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17324932 17324932]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transition state analogue]]
[[Category: transition state analogue]]


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