2b8t: Difference between revisions

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[[Image:2b8t.gif|left|200px]]<br /><applet load="2b8t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2b8t.gif|left|200px]]
caption="2b8t, resolution 2.00&Aring;" />
 
'''Crystal structure of Thymidine Kinase from U.urealyticum in complex with thymidine'''<br />
{{Structure
|PDB= 2b8t |SIZE=350|CAPTION= <scene name='initialview01'>2b8t</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21]
|GENE= tdk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=134821 Ureaplasma parvum])
}}
 
'''Crystal structure of Thymidine Kinase from U.urealyticum in complex with thymidine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2B8T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ureaplasma_parvum Ureaplasma parvum] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=THM:'>THM</scene> and <scene name='pdbligand=TRS:'>TRS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B8T OCA].  
2B8T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ureaplasma_parvum Ureaplasma parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B8T OCA].  


==Reference==
==Reference==
Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme., Kosinska U, Carnrot C, Eriksson S, Wang L, Eklund H, FEBS J. 2005 Dec;272(24):6365-72. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16336273 16336273]
Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme., Kosinska U, Carnrot C, Eriksson S, Wang L, Eklund H, FEBS J. 2005 Dec;272(24):6365-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16336273 16336273]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Thymidine kinase]]
[[Category: Thymidine kinase]]
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[[Category: zinc-binding domain]]
[[Category: zinc-binding domain]]


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