2b9a: Difference between revisions
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[[Image:2b9a.gif|left|200px]] | [[Image:2b9a.gif|left|200px]] | ||
'''Human transthyretin (TTR) complexed with diflunisal analogues- TTR.3',5'-difluorobiphenyl-4-carboxylic acid''' | {{Structure | ||
|PDB= 2b9a |SIZE=350|CAPTION= <scene name='initialview01'>2b9a</scene>, resolution 1.54Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=FBC:3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID'>FBC</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''Human transthyretin (TTR) complexed with diflunisal analogues- TTR.3',5'-difluorobiphenyl-4-carboxylic acid''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2B9A is a [ | 2B9A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B9A OCA]. | ||
==Reference== | ==Reference== | ||
Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis., Adamski-Werner SL, Palaninathan SK, Sacchettini JC, Kelly JW, J Med Chem. 2004 Jan 15;47(2):355-74. PMID:[http:// | Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis., Adamski-Werner SL, Palaninathan SK, Sacchettini JC, Kelly JW, J Med Chem. 2004 Jan 15;47(2):355-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14711308 14711308] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: ttr]] | [[Category: ttr]] | ||
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