3gkl: Difference between revisions

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{{STRUCTURE_3gkl|  PDB=3gkl  |  SCENE=  }}
==Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins==
===Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins===
<StructureSection load='3gkl' size='340' side='right' caption='[[3gkl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
{{ABSTRACT_PUBMED_019749752}}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3gkl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GKL FirstGlance]. <br>
==About this Structure==
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[3gkl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKL OCA].  
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gjn|3gjn]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">colE7, cea ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), imm, ceiE9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gkl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gkl RCSB], [http://www.ebi.ac.uk/pdbsum/3gkl PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/3gkl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
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*[[Mutant immunity protein 9 (variant R12-13)|Mutant immunity protein 9 (variant R12-13)]]
*[[Mutant immunity protein 9 (variant R12-13)|Mutant immunity protein 9 (variant R12-13)]]
*[[Mutant immunity protein 9 (variant R12-2)|Mutant immunity protein 9 (variant R12-2)]]
*[[Mutant immunity protein 9 (variant R12-2)|Mutant immunity protein 9 (variant R12-2)]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019749752</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Dym, O.]]
[[Category: Dym, O]]
[[Category: ISPC, Israel Structural Proteomics Center.]]
[[Category: ISPC, Israel Structural Proteomics Center]]
[[Category: Tawfik, D S.]]
[[Category: Tawfik, D S]]
[[Category: Antibiotic]]
[[Category: Antibiotic]]
[[Category: Antimicrobial]]
[[Category: Antimicrobial]]
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[[Category: Endonuclease]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: ISPC]]
[[Category: Israel Structural Proteomics Center]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Nuclease]]
[[Category: Nuclease]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]