3omv: Difference between revisions

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Revision as of 09:40, 11 March 2013

Template:STRUCTURE 3omv

Crystal structure of c-raf (raf-1)

Template:ABSTRACT PUBMED 20130576

About this Structure

3omv is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3lb7. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature. 2010 Mar 18;464(7287):431-5. Epub 2010 Feb 3. PMID:20130576 doi:10.1038/nature08833

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