1q2l: Difference between revisions
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==Crystal Structure of pitrilysin== | |||
<StructureSection load='1q2l' size='340' side='right' caption='[[1q2l]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1q2l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_str._k-12_substr._w3110 Escherichia coli str. k-12 substr. w3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q2L FirstGlance]. <br> | ||
[[1q2l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_str._k-12_substr._w3110 Escherichia coli str. k-12 substr. w3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2L OCA]. | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pitrilysin Pitrilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.55 3.4.24.55] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q2l RCSB], [http://www.ebi.ac.uk/pdbsum/1q2l PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PTRA_ECOLI PTRA_ECOLI]] Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q2/1q2l_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Metalloproteases|Metalloproteases]] | *[[Metalloproteases|Metalloproteases]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli str. k-12 substr. w3110]] | [[Category: Escherichia coli str. k-12 substr. w3110]] | ||
[[Category: Pitrilysin]] | [[Category: Pitrilysin]] | ||
[[Category: Fernandez-Catalan, C | [[Category: Fernandez-Catalan, C]] | ||
[[Category: Jozic, D | [[Category: Jozic, D]] | ||
[[Category: Maskos, K | [[Category: Maskos, K]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
