3pla: Difference between revisions

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~~{{STRUCTURE_3pla| PDB=3pla | SCENE= }}~~

==Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus==

===Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus===

== Structural highlights ==

==~~About this Structure~~==

<table><tr><td colspan='2'>[[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PLA FirstGlance].

[[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), rpl7ae, Ssol_1068 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pla RCSB], [http://www.ebi.ac.uk/pdbsum/3pla PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref> [[http://www.uniprot.org/uniprot/D0KRE2_SULS9 D0KRE2_SULS9]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326]

==See Also==

*[[Kink-turn motif|Kink-turn motif]]

*[[Ribosomal protein L7|Ribosomal protein L7]]

*[[Sandbox3pla|Sandbox3pla]]

*[[User:Wayne Decatur/NASCE2011|User:Wayne Decatur/NASCE2011]]

*[[User:Wayne Decatur/UNH CME Workshop March 11 2011|User:Wayne Decatur/UNH CME Workshop March 11 2011]]

*[[User:Wayne Decatur/UNH Seminar Feb 1st 2011|User:Wayne Decatur/UNH Seminar Feb 1st 2011]]

*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]

== References ==

__TOC__

</StructureSection>

[[Category: Sulfolobus solfataricus]]

[[Category: Jia, R.]]

[[Category: Jia, R]]

[[Category: Lai, S.]]

[[Category: Lai, S]]

[[Category: Lin, J.]]

[[Category: Lin, J]]

[[Category: Lu, J.]]

[[Category: Lu, J]]

[[Category: Xu, A.]]

[[Category: Xu, A]]

[[Category: Ye, K.]]

[[Category: Ye, K]]

[[Category: Zhang, L.]]

[[Category: Zhang, L]]

[[Category: Box c/d rna]]

[[Category: Guide rna]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3pla|  PDB=3pla  |  SCENE=  }}
+==Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus==
-===Crystal structure of a catalytically active substrate-bound box C/D RNP from Sulfolobus solfataricus===
+<StructureSection load='3pla' size='340' side='right' caption='[[3pla]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PLA FirstGlance]. <br>
-[[3pla]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLA OCA].
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), rpl7ae, Ssol_1068 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pla OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pla RCSB], [http://www.ebi.ac.uk/pdbsum/3pla PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>  [[http://www.uniprot.org/uniprot/D0KRE2_SULS9 D0KRE2_SULS9]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326]
 ==See Also==
 *[[Kink-turn motif|Kink-turn motif]]
 *[[Ribosomal protein L7|Ribosomal protein L7]]
-*[[Sandbox3pla|Sandbox3pla]]
 *[[User:Wayne Decatur/NASCE2011|User:Wayne Decatur/NASCE2011]]
 *[[User:Wayne Decatur/UNH CME Workshop March 11 2011|User:Wayne Decatur/UNH CME Workshop March 11 2011]]
 *[[User:Wayne Decatur/UNH Seminar Feb 1st 2011|User:Wayne Decatur/UNH Seminar Feb 1st 2011]]
 *[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Sulfolobus solfataricus]]
-[[Category: Jia, R.]]
+[[Category: Jia, R]]
-[[Category: Lai, S.]]
+[[Category: Lai, S]]
-[[Category: Lin, J.]]
+[[Category: Lin, J]]
-[[Category: Lu, J.]]
+[[Category: Lu, J]]
-[[Category: Xu, A.]]
+[[Category: Xu, A]]
-[[Category: Ye, K.]]
+[[Category: Ye, K]]
-[[Category: Zhang, L.]]
+[[Category: Zhang, L]]
 [[Category: Box c/d rna]]
 [[Category: Guide rna]]