1usx: Difference between revisions
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{{STRUCTURE_1usx| PDB=1usx | SCENE= }} | {{STRUCTURE_1usx| PDB=1usx | SCENE= }} | ||
=== | ===Crystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialoside=== | ||
{{ABSTRACT_PUBMED_15016893}} | {{ABSTRACT_PUBMED_15016893}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/HN_NDVB HN_NDVB]] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[1usx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[1usx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_type_1 Avian paramyxovirus type 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1USX OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:015016893</ref>< | <ref group="xtra">PMID:015016893</ref><references group="xtra"/><references/> | ||
[[Category: Avian paramyxovirus type 1]] | |||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
[[Category: Groves, D.]] | [[Category: Groves, D.]] | ||
[[Category: Itzstein, M | [[Category: Itzstein, M.]] | ||
[[Category: Kiefel, M.]] | [[Category: Kiefel, M.]] | ||
[[Category: Portner, A.]] | [[Category: Portner, A.]] | ||
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[[Category: Zaitsev, V.]] | [[Category: Zaitsev, V.]] | ||
[[Category: Hemagglutinin]] | [[Category: Hemagglutinin]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Neuraminidase]] | [[Category: Neuraminidase]] | ||
[[Category: Sialidase]] | [[Category: Sialidase]] | ||
