1ax8: Difference between revisions
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===Human obesity protein, leptin=== | ===Human obesity protein, leptin=== | ||
{{ABSTRACT_PUBMED_9144295}} | {{ABSTRACT_PUBMED_9144295}} | ||
==Disease== | |||
[[http://www.uniprot.org/uniprot/LEP_HUMAN LEP_HUMAN]] Defects in LEP may be a cause of obesity (OBESITY) [MIM:[http://omim.org/entry/601665 601665]]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.<ref>PMID:9500540</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LEP_HUMAN LEP_HUMAN]] May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:009144295</ref><ref group="xtra">PMID:011742118</ref><references group="xtra"/> | <ref group="xtra">PMID:009144295</ref><ref group="xtra">PMID:011742118</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Leptin]] | [[Category: Leptin]] | ||
