3zm9: Difference between revisions
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===The mechanism of allosteric coupling in choline kinase a1 revealed by a rationally designed inhibitor=== | ===The mechanism of allosteric coupling in choline kinase a1 revealed by a rationally designed inhibitor=== | ||
{{ABSTRACT_PUBMED_23441033}} | {{ABSTRACT_PUBMED_23441033}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN]] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3zm9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM9 OCA]. | [[3zm9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM9 OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Conejo-Garcia, A.]] | [[Category: Conejo-Garcia, A.]] | ||
