3zgo: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_3zgo|  PDB=3zgo  |  SCENE=  }}
+===Re-refined structure of the human Sirt2 apoform===
+{{ABSTRACT_PUBMED_11427894}}
-The entry 3zgo is ON HOLD  until sometime in the future
+==Function==
+[[http://www.uniprot.org/uniprot/SIR2_HUMAN SIR2_HUMAN]] NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.<ref>PMID:12620231</ref> <ref>PMID:12697818</ref> <ref>PMID:21081649</ref> <ref>PMID:21726808</ref>
-Authors: Moniot, S., Steegborn, C.
+==About this Structure==
+[[3zgo]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZGO OCA].
-Description: Re-refined structure of the human Sirt2 apoform
+==Reference==
+<ref group="xtra">PMID:011427894</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Moniot, S.]]
+[[Category: Steegborn, C.]]
+[[Category: Hydrolase]]
+[[Category: Nad+-dependent deacetylase]]
+[[Category: Sirtuin]]

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