4ixh: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4ixh| PDB=4ixh | SCENE= }} | |||
===Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IMDH_CRYPV IMDH_CRYPV]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).<ref>PMID:15269207</ref> | |||
==About this Structure== | |||
[[4ixh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXH OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Cryptosporidium parvum]] | |||
[[Category: IMP dehydrogenase]] | |||
[[Category: Andesrson, W F.]] | |||
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]] | |||
[[Category: Gu, M.]] | |||
[[Category: Hedstrom, L.]] | |||
[[Category: Joachimiak, A.]] | |||
[[Category: Kavitha, M.]] | |||
[[Category: Kim, Y.]] | |||
[[Category: Makowska-Grzyska, M.]] | |||
[[Category: Alpha-beta fold]] | |||
[[Category: Center for structural genomics of infectious disease]] | |||
[[Category: Csgid]] | |||
[[Category: National institute of allergy and infectious disease]] | |||
[[Category: Niaid]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Structural genomic]] | |||
[[Category: Tim barrel]] | |||
Revision as of 01:52, 4 April 2013
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum
Function
[IMDH_CRYPV] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[1]
About this Structure
4ixh is a 4 chain structure with sequence from Cryptosporidium parvum. Full crystallographic information is available from OCA.
Reference
- ↑ Umejiego NN, Li C, Riera T, Hedstrom L, Striepen B. Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design. J Biol Chem. 2004 Sep 24;279(39):40320-7. Epub 2004 Jul 21. PMID:15269207 doi:10.1074/jbc.M407121200
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Cryptosporidium parvum
- IMP dehydrogenase
- Andesrson, W F.
- CSGID, Center for Structural Genomics of Infectious Diseases.
- Gu, M.
- Hedstrom, L.
- Joachimiak, A.
- Kavitha, M.
- Kim, Y.
- Makowska-Grzyska, M.
- Alpha-beta fold
- Center for structural genomics of infectious disease
- Csgid
- National institute of allergy and infectious disease
- Niaid
- Oxidoreductase
- Structural genomic
- Tim barrel
