3ikr: Difference between revisions
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===Crystal structure of alpha 1-4 mannobiose bound trimeric human lung surfactant protein D=== | ===Crystal structure of alpha 1-4 mannobiose bound trimeric human lung surfactant protein D=== | ||
{{ABSTRACT_PUBMED_19799916}} | {{ABSTRACT_PUBMED_19799916}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | |||
==About this Structure== | ==About this Structure== | ||
[[3ikr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ikr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKR OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019799916</ref>< | <ref group="xtra">PMID:019799916</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Greenhough, T J.]] | [[Category: Greenhough, T J.]] | ||
[[Category: Shrive, A K.]] | [[Category: Shrive, A K.]] | ||
Revision as of 14:17, 19 February 2014
Crystal structure of alpha 1-4 mannobiose bound trimeric human lung surfactant protein D
Template:ABSTRACT PUBMED 19799916
Function
[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
About this Structure
3ikr is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Shrive AK, Martin C, Burns I, Paterson JM, Martin JD, Townsend JP, Waters P, Clark HW, Kishore U, Reid KB, Greenhough TJ. Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325. J Mol Biol. 2009 Dec 11;394(4):776-88. Epub 2009 Sep 30. PMID:19799916 doi:10.1016/j.jmb.2009.09.057
