3idp: Difference between revisions

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Revision as of 11:02, 13 March 2013

Template:STRUCTURE 3idp

B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor

Template:ABSTRACT PUBMED 19764794

About this Structure

3idp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g

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