4bel: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4bel|  PDB=4bel  |  SCENE=  }}
===BACE2 XAPERONE COMPLEX===
{{ABSTRACT_PUBMED_23695257}}


The entry 4bel is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/BACE2_HUMAN BACE2_HUMAN]] Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.<ref>PMID:10591213</ref> <ref>PMID:11083922</ref> <ref>PMID:15857888</ref> <ref>PMID:11423558</ref> <ref>PMID:16816112</ref>  


Authors: Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A.
==About this Structure==
[[4bel]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEL OCA].  


Description: BACE2 XAPERONE COMPLEX
==Reference==
<ref group="xtra">PMID:023695257</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Memapsin 1]]
[[Category: Banner, D W.]]
[[Category: Benz, J.]]
[[Category: Kuglstatter, A.]]
[[Category: Ruf, A.]]
[[Category: Stihle, M.]]
[[Category: Hydrolase-immune system complex]]
[[Category: Nanobody]]