4dxx: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4dxx|  PDB=4dxx  |  SCENE=  }}
===TGT K52M mutant crystallized at pH 8.5===


The entry 4dxx is ON HOLD  until Mar 27 2014
==Function==
[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]


Authors: Jakobi, S., Ritschel, T., Heine, A., Klebe, G.
==About this Structure==
 
[[4dxx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXX OCA].  
Description: TGT K52M mutant crystallized at pH 8.5
[[Category: Zymomonas mobilis]]
[[Category: Heine, A.]]
[[Category: Jakobi, S.]]
[[Category: Klebe, G.]]
[[Category: Ritschel, T.]]
[[Category: Dimer interface]]
[[Category: Functional dimer]]
[[Category: Guanine binding]]
[[Category: Guanine exchange enzyme]]
[[Category: Transferase]]
[[Category: Trna binding]]
[[Category: Zinc binding]]