4ia0: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4ia0|  PDB=4ia0  |  SCENE=  }}
===Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors===
{{ABSTRACT_PUBMED_23867165}}


The entry 4ia0 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.


Authors: Ren, J., Chen, T.T., Xu, Y.C.
==About this Structure==
[[4ia0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IA0 OCA].  


Description: Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors
==Reference==
<ref group="xtra">PMID:023867165</ref><references group="xtra"/><references/>
[[Category: 3',5'-cyclic-GMP phosphodiesterase]]
[[Category: Chen, T.]]
[[Category: Ren, J.]]
[[Category: Xu, Y.]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]