4ia0: Difference between revisions
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{{STRUCTURE_4ia0| PDB=4ia0 | SCENE= }} | |||
===Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors=== | |||
{{ABSTRACT_PUBMED_23867165}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PDE5A_HUMAN PDE5A_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. | |||
==About this Structure== | |||
[[4ia0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IA0 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023867165</ref><references group="xtra"/><references/> | |||
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | |||
[[Category: Chen, T.]] | |||
[[Category: Ren, J.]] | |||
[[Category: Xu, Y.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||