2c31: Difference between revisions

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[[Image:2c31.gif|left|200px]]<br /><applet load="2c31" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2c31.gif|left|200px]]
caption="2c31, resolution 1.73&Aring;" />
 
'''CRYSTAL STRUCTURE OF OXALYL-COA DECARBOXYLASE IN COMPLEX WITH THE COFACTOR DERIVATIVE THIAMIN-2-THIAZOLONE DIPHOSPHATE AND ADENOSINE DIPHOSPHATE'''<br />
{{Structure
|PDB= 2c31 |SIZE=350|CAPTION= <scene name='initialview01'>2c31</scene>, resolution 1.73&Aring;
|SITE= <scene name='pdbsite=AC1:Adp+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TZD:2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TZD</scene> and <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Oxalyl-CoA_decarboxylase Oxalyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.8 4.1.1.8]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF OXALYL-COA DECARBOXYLASE IN COMPLEX WITH THE COFACTOR DERIVATIVE THIAMIN-2-THIAZOLONE DIPHOSPHATE AND ADENOSINE DIPHOSPHATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2C31 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oxalobacter_formigenes Oxalobacter formigenes] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=TZD:'>TZD</scene> and <scene name='pdbligand=ADP:'>ADP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Oxalyl-CoA_decarboxylase Oxalyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.8 4.1.1.8] Known structural/functional Site: <scene name='pdbsite=AC1:Adp+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C31 OCA].  
2C31 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oxalobacter_formigenes Oxalobacter formigenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C31 OCA].  


==Reference==
==Reference==
Structural basis for activation of the thiamin diphosphate-dependent enzyme oxalyl-CoA decarboxylase by adenosine diphosphate., Berthold CL, Moussatche P, Richards NG, Lindqvist Y, J Biol Chem. 2005 Dec 16;280(50):41645-54. Epub 2005 Oct 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16216870 16216870]
Structural basis for activation of the thiamin diphosphate-dependent enzyme oxalyl-CoA decarboxylase by adenosine diphosphate., Berthold CL, Moussatche P, Richards NG, Lindqvist Y, J Biol Chem. 2005 Dec 16;280(50):41645-54. Epub 2005 Oct 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16216870 16216870]
[[Category: Oxalobacter formigenes]]
[[Category: Oxalobacter formigenes]]
[[Category: Oxalyl-CoA decarboxylase]]
[[Category: Oxalyl-CoA decarboxylase]]
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[[Category: thiamine pyrophosphate]]
[[Category: thiamine pyrophosphate]]


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