2cmo: Difference between revisions

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[[Image:2cmo.gif|left|200px]]<br /><applet load="2cmo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2cmo.gif|left|200px]]
caption="2cmo, resolution 2.65&Aring;" />
 
'''THE STRUCTURE OF A MIXED GLUR2 LIGAND-BINDING CORE DIMER IN COMPLEX WITH (S)-GLUTAMATE AND THE ANTAGONIST (S)-NS1209'''<br />
{{Structure
|PDB= 2cmo |SIZE=350|CAPTION= <scene name='initialview01'>2cmo</scene>, resolution 2.65&Aring;
|SITE= <scene name='pdbsite=AC1:M1l+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene> and <scene name='pdbligand=M1L:2-({[(3E)-5-{4-[(DIMETHYLAMINO)(DIHYDROXY)-LAMBDA~4~-SULFANYL]PHENYL}-8-METHYL-2-OXO-6,7,8,9-TETRAHYDRO-1H-PYRROLO[3,2-H]ISOQUINOLIN-3(2H)-YLIDENE]AMINO}OXY)-4-HYDROXYBUTANOIC ACID'>M1L</scene>
|ACTIVITY=
|GENE=
}}
 
'''THE STRUCTURE OF A MIXED GLUR2 LIGAND-BINDING CORE DIMER IN COMPLEX WITH (S)-GLUTAMATE AND THE ANTAGONIST (S)-NS1209'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CMO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=GLU:'>GLU</scene> and <scene name='pdbligand=M1L:'>M1L</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:M1l+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMO OCA].  
2CMO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMO OCA].  


==Reference==
==Reference==
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209., Kasper C, Pickering DS, Mirza O, Olsen L, Kristensen AS, Greenwood JR, Liljefors T, Schousboe A, Watjen F, Gajhede M, Sigurskjold BW, Kastrup JS, J Mol Biol. 2006 Apr 7;357(4):1184-201. Epub 2006 Jan 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16483599 16483599]
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209., Kasper C, Pickering DS, Mirza O, Olsen L, Kristensen AS, Greenwood JR, Liljefors T, Schousboe A, Watjen F, Gajhede M, Sigurskjold BW, Kastrup JS, J Mol Biol. 2006 Apr 7;357(4):1184-201. Epub 2006 Jan 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16483599 16483599]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transport]]
[[Category: transport]]


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