3h7d: Difference between revisions
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{{STRUCTURE_3h7d| PDB=3h7d | SCENE= }} | {{STRUCTURE_3h7d| PDB=3h7d | SCENE= }} | ||
===The crystal structure of the cathepsin K Variant M5 in complex with chondroitin-4-sulfate=== | ===The crystal structure of the cathepsin K Variant M5 in complex with chondroitin-4-sulfate=== | ||
{{ | {{ABSTRACT_PUBMED_21193413}} | ||
==Disease== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CATK_HUMAN CATK_HUMAN]] Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:[http://omim.org/entry/265800 265800]]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.<ref>PMID:8703060</ref><ref>PMID:9529353</ref><ref>PMID:10491211</ref><ref>PMID:10878663</ref> | [[http://www.uniprot.org/uniprot/CATK_HUMAN CATK_HUMAN]] Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:[http://omim.org/entry/265800 265800]]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.<ref>PMID:8703060</ref> <ref>PMID:9529353</ref> <ref>PMID:10491211</ref> <ref>PMID:10878663</ref> | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[3h7d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3h7d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H7D OCA]. | ||
==See Also== | ==See Also== | ||
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<ref group="xtra">PMID:021193413</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:021193413</ref><references group="xtra"/><references/> | ||
[[Category: Cathepsin K]] | [[Category: Cathepsin K]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Bromme, D.]] | [[Category: Bromme, D.]] | ||
[[Category: Cherney, M M.]] | [[Category: Cherney, M M.]] | ||
