2dc3: Difference between revisions
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[[Image:2dc3.gif|left|200px]] | [[Image:2dc3.gif|left|200px]] | ||
'''Crystal structure of human cytoglobin at 1.68 angstroms resolution''' | {{Structure | ||
|PDB= 2dc3 |SIZE=350|CAPTION= <scene name='initialview01'>2dc3</scene>, resolution 1.68Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene> | |||
|ACTIVITY= | |||
|GENE= CYGB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of human cytoglobin at 1.68 angstroms resolution''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2DC3 is a [ | 2DC3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DC3 OCA]. | ||
==Reference== | ==Reference== | ||
High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:[http:// | High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16699195 16699195] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: riken structural genomics/proteomics initiative]] | [[Category: riken structural genomics/proteomics initiative]] | ||
[[Category: rsgi]] | [[Category: rsgi]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:25:29 2008'' | ||
Revision as of 14:25, 20 March 2008
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| 2dc3, resolution 1.68Å | |||||||||||||
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| Ligands: | HEM and ACY | ||||||||||||
| Gene: | CYGB (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of human cytoglobin at 1.68 angstroms resolution
Overview
Cytoglobin (Cgb) is a recently discovered member of the vertebrate haem-containing globin family. The structure of a new crystal form of wild-type human Cgb (space group C2) was determined at a resolution of 1.68 Angstrom. The results show the presence of an additional helix in the N-terminal residues (4-20) prior to the A helix and an ordered loop structure in the C-terminal region (168-188), while these extended peptides were invisible owing to disorder in the previously reported structures using a P3(2)21 crystal at a resolution of 2.4 Angstrom. A detailed comparison of the two crystal structures shows differences in the conformation of the residues (i.e. Arg84) in the haem environment owing to a different dimeric arrangement.
About this Structure
2DC3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:16699195
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