2m5v: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2m5v|  PDB=2m5v  |  SCENE=  }}
===Three-dimensional structure of human NLRP10/PYNOD pyrin domain===
{{ABSTRACT_PUBMED_22618865}}


The entry 2m5v is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/NAL10_HUMAN NAL10_HUMAN]] Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.<ref>PMID:15096476</ref> <ref>PMID:20393137</ref> <ref>PMID:22672233</ref>  


Authors: Su, M.Y., Chang, C.F., Chang, C.I.
==About this Structure==
[[2m5v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5V OCA].  


Description: Three-dimensional structure of human NLRP10/PYNOD pyrin domain
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Chang, C F.]]
[[Category: Chang, C I.]]
[[Category: Su, M Y.]]
[[Category: Immune system]]
[[Category: Nlrp10]]
[[Category: Pynod]]
[[Category: Pyrin domain]]
Retrieved from "https://proteopedia.org/2m5v"