4jgw: Difference between revisions
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{{STRUCTURE_4jgw| PDB=4jgw | SCENE= }} | |||
===The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf=== | |||
{{ABSTRACT_PUBMED_23891840}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RGL2_MOUSE RGL2_MOUSE]] Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro. | |||
==About this Structure== | |||
[[4jgw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023891840</ref><references group="xtra"/><references/> | |||
[[Category: Mus musculus]] | |||
[[Category: Jakobi, A J.]] | |||
[[Category: Popovic, M.]] | |||
[[Category: Rehmann, H.]] | |||
[[Category: Cdc25-homology domain]] | |||
[[Category: Guanine nucleotide exchange factor]] | |||
[[Category: Rem-domain]] | |||
[[Category: Sh3 domain binding]] | |||
[[Category: Signaling protein]] | |||
[[Category: Small g-protein binding]] | |||
Revision as of 05:24, 12 September 2013
The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf
Template:ABSTRACT PUBMED 23891840
Function
[RGL2_MOUSE] Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
About this Structure
4jgw is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Popovic M, Jakobi AJ, Rensen-de Leeuw M, Rehmann H. The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation. J Struct Biol. 2013 Sep;183(3):312-9. doi: 10.1016/j.jsb.2013.07.009. Epub 2013, Jul 24. PMID:23891840 doi:10.1016/j.jsb.2013.07.009
