4jql: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jql|  PDB=4jql  |  SCENE=  }}
===Synthesis of Benzoquinone-Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid===


The entry 4jql is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> 


Authors: Jeso, V., Iqbal, S., Hernandez, P., Cameron, M.D., Park, H., Lograsso, P.V., Micalizio, G.C.
==About this Structure==
[[4jql]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQL OCA].  


Description: Synthesis of Benzoquinone-Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Cameron, M D.]]
[[Category: Hernandez, P.]]
[[Category: Iqbal, S.]]
[[Category: Jeso, V.]]
[[Category: Lograsso, P V.]]
[[Category: Micalizio, G C.]]
[[Category: Park, H.]]
[[Category: Chaperone]]
[[Category: Chaperone-inhibitor complex]]
[[Category: Cytosole]]
[[Category: Geldanamycin]]
[[Category: Hsp90]]
[[Category: Inhibitor design]]
[[Category: Nucleotide binding domain]]