4jql: Difference between revisions
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{{STRUCTURE_4jql| PDB=4jql | SCENE= }} | |||
===Synthesis of Benzoquinone-Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | |||
==About this Structure== | |||
[[4jql]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQL OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Cameron, M D.]] | |||
[[Category: Hernandez, P.]] | |||
[[Category: Iqbal, S.]] | |||
[[Category: Jeso, V.]] | |||
[[Category: Lograsso, P V.]] | |||
[[Category: Micalizio, G C.]] | |||
[[Category: Park, H.]] | |||
[[Category: Chaperone]] | |||
[[Category: Chaperone-inhibitor complex]] | |||
[[Category: Cytosole]] | |||
[[Category: Geldanamycin]] | |||
[[Category: Hsp90]] | |||
[[Category: Inhibitor design]] | |||
[[Category: Nucleotide binding domain]] | |||