3jtp: Difference between revisions

Line 1:

~~{{STRUCTURE_3jtp| PDB=3jtp | SCENE= }}~~

==crystal structure of the C-terminal domain of MecA==

===crystal structure of the C-terminal domain of MecA===

~~{{ABSTRACT_PUBMED_019801546}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTP FirstGlance]. <br>

==~~Function~~==

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>

[[~~http://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU~~]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, ~~inhibits sporulation~~. ~~Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref~~>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jtn|3jtn]], [[3jto|3jto]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mecA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>

==~~About this Structure~~==

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [http://www.ebi.ac.uk/pdbsum/3jtp PDBsum]</span></td></tr>

[[3jtp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA].

</table>

== Evolutionary Conservation ==

==~~Reference~~==

[[Image:Consurf_key_small.gif|200px|right]]

<~~references group~~="~~xtra~~"/><~~references~~/>

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtp_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

__TOC__

</StructureSection>

[[Category: Bacillus subtilis]]

[[Category: Mei, Z.]]

[[Category: Mei, Z]]

[[Category: Qi, Y.]]

[[Category: Qi, Y]]

[[Category: Shi, Y.]]

[[Category: Shi, Y]]

[[Category: Wang, F.]]

[[Category: Wang, F]]

[[Category: Wang, J.]]

[[Category: Wang, J]]

[[Category: Yan, C.]]

[[Category: Yan, C]]

[[Category: Adaptor protein]]

[[Category: Competence]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3jtp|  PDB=3jtp  |  SCENE=  }}
+==crystal structure of the C-terminal domain of MecA==
-===crystal structure of the C-terminal domain of MecA===
+<StructureSection load='3jtp' size='340' side='right' caption='[[3jtp]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
-{{ABSTRACT_PUBMED_019801546}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTP FirstGlance]. <br>
-==Function==
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-[[http://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jtn|3jtn]], [[3jto|3jto]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mecA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [http://www.ebi.ac.uk/pdbsum/3jtp PDBsum]</span></td></tr>
-[[3jtp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA].
+</table>
+== Evolutionary Conservation ==
-==Reference==
+[[Image:Consurf_key_small.gif|200px|right]]
-<references group="xtra"/><references/>
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Bacillus subtilis]]
-[[Category: Mei, Z.]]
+[[Category: Mei, Z]]
-[[Category: Qi, Y.]]
+[[Category: Qi, Y]]
-[[Category: Shi, Y.]]
+[[Category: Shi, Y]]
-[[Category: Wang, F.]]
+[[Category: Wang, F]]
-[[Category: Wang, J.]]
+[[Category: Wang, J]]
-[[Category: Yan, C.]]
+[[Category: Yan, C]]
 [[Category: Adaptor protein]]
 [[Category: Competence]]